Darcy B Adin

Darcy B Adin, DVM, DACVIM (Cardiology)

Small Animal Hospital Chief Medical Officer, Clinical Professor – Cardiology

Department: Small Animal Clinical Sciences
Business Phone: (352) 392-2229
Business Email: adind@ufl.edu

About Darcy B Adin

Hi! My name is Dr. Darcy Adin. I am a board-certified veterinary cardiologist at the Small Animal Hospital at the University of Florida, College of Veterinary Medicine where I work as a clinician and also as the Chief Medical Officer. I treat all animals with heart disease, and I am especially passionate about improving the lives of dogs living with degenerative mitral valve disease and congestive heart failure. My areas of interest and clinical research focus on improving our understanding of heart failure so we can optimize medical treatments for pets affected with this common disease. I also serve as the Director of the Open-Heart Surgery Program at the Small Animal Hospital, which through the expertise of Dr. Katsuhiro Matsuura provides surgical treatment to repair the mitral valve of dogs affected with degenerative mitral valve disease.

Related Links:

Accomplishments

FVMA Clinical Investigator Award
2022 · Florida Veterinary Medical Association

Teaching Profile

Courses Taught
2019-2023
VEM5301 Cardiopul Disorders
2018-2025
VEM5862 Vet Cardio Clerkship
2019-2020
VEM5111 Animal Systems 2
2021-2025
VEM5286 Vet Clin Pharmacology
2021-2024
VEM5991 Clkship Indiv Invest
Teaching Philosophy
I believe in a multifaceted teaching approach to solidify important principles for success in clinical practice while simultaneously laying the foundation for success on necessary board examinations. This involves hands on learning (e.g. making sure my students hear heart murmurs on their patients), evidenced-based learning (e.g. looking up published studies to guide treatment choices), and clinically oriented rounds learning (e.g. discussing real-life case scenarios and the spectrum of ways to handle them depending on the situation). In each of the clinical or classroom settings and regardless of whether I am teaching students or veterinary residents, I try to create a safe environment where questions are invited and critical thinking is encouraged. I strive to instill a love of learning in my students and residents so that they embrace a life-long learning approach to veterinary medicine.

Board Certifications

  • Cardiology
    American College of Veterinary Internal Medicine

Clinical Profile

Areas of Interest
  • Heart Failure
  • Mitral valve regurgitation

Research Profile

My research is focused on the goal of improving the lives of pets living with heart disease through clinical discovery. To this end and with the collaboration of other researchers, I have reported on aspects such as refining the use of diuretics for heart failure treatment, the role of the kidney as it relates to heart disease, understanding factors that influence neurohormonal systems such as the renin-angiotensin-aldosterone system in heart disease, and improving our understanding of refractory heart failure so treatments can be effectively targeted to abnormalities. I am especially interested in elucidating the effect of electrolyte disturbances on disease progression and determining if we can intervene medically to improve outcomes. Heart disease is very common in dogs and cats, and while we have many new exciting medical and surgical options available, it is important that we continue clinical research efforts to better understand and treat pets with heart disease.

Areas of Interest
  • Evaluation of the Renin-Angiotensin-Aldosterone system
  • Nutritionally mediated Dilated Cardiomyopathy
  • Optimization of diuretic therapy for congestive heart failure
Open Researcher and Contributor ID (ORCID)

0000-0003-0972-0365

Publications

2024
Efficacy of a mitral regurgitation severity index to predict long‐term outcome in dogs with myxomatous mitral valve disease
Journal of Veterinary Internal Medicine. 38(1):51-60 [DOI] 10.1111/jvim.16923. [PMID] 37909399.
2023
Angiotensin-converting enzyme 2 in dogs with Dirofilaria immitis.
Parasites & vectors. 16(1) [DOI] 10.1186/s13071-023-05649-9. [PMID] 37106412.
2023
Beyond Angiotensin-Converting Enzyme Inhibitors: Modulation of the Renin-Angiotensin-Aldosterone System to Delay or Manage Congestive Heart Failure.
The Veterinary clinics of North America. Small animal practice. 53(6):1353-1366 [DOI] 10.1016/j.cvsm.2023.05.015. [PMID] 37423846.
2023
Evaluation of Renin–Angiotensin–Aldosterone System Components and Enzymes in Systemically Hypertensive Cats Receiving Amlodipine
Animals. 13(22) [DOI] 10.3390/ani13223479. [PMID] 38003097.
2023
Influence of sex on renin‐angiotensin‐aldosterone system metabolites and enzymes in Doberman Pinschers
Journal of Veterinary Internal Medicine. 37(1):22-27 [DOI] 10.1111/jvim.16589. [PMID] 36412252.
2023
Myocardial Enhancement Following Agitated Saline Contrast Study in a Boxer Dog
CASE. 7(7):292-294 [DOI] 10.1016/j.case.2023.02.009. [PMID] 37546359.
2023
The effect of taurine supplementation on the renin-angiotensin-aldosterone system of dogs with congestive heart failure.
Scientific reports. 13(1) [DOI] 10.1038/s41598-023-37978-1. [PMID] 37400490.
2023
Toward quantification of loop diuretic responsiveness for congestive heart failure
Journal of Veterinary Internal Medicine. 37(1):12-21 [DOI] 10.1111/jvim.16590. [PMID] 36408832.
2023
Use of serum osmolality to identify heart disease stage in dogs and relationship to mathematical chloride correction
Journal of Veterinary Internal Medicine. 37(6):2011-2020 [DOI] 10.1111/jvim.16863. [PMID] 37702389.
2022
Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 40:99-109 [DOI] 10.1016/j.jvc.2021.02.001. [PMID] 33741312.
2022
Canine cardiomyopathies.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 40 [DOI] 10.1016/j.jvc.2021.12.008. [PMID] 35016852.
2022
Effect of diet change in healthy dogs with subclinical cardiac biomarker or echocardiographic abnormalities
Journal of Veterinary Internal Medicine. 36(3):1057-1065 [DOI] 10.1111/jvim.16416. [PMID] 35420218.
2022
Metabolomic profiling in dogs with dilated cardiomyopathy eating non-traditional or traditional diets and in healthy controls.
Scientific reports. 12(1) [DOI] 10.1038/s41598-022-26322-8. [PMID] 36585421.
2022
Prospective study of dilated cardiomyopathy in dogs eating nontraditional or traditional diets and in dogs with subclinical cardiac abnormalities
Journal of Veterinary Internal Medicine. 36(2):451-463 [DOI] 10.1111/jvim.16397. [PMID] 35297103.
2022
Retrospective evaluation of risk factors for development of kidney injury after parenteral furosemide treatment of left‐sided congestive heart failure in dogs
Journal of Veterinary Internal Medicine. 36(6):2042-2052 [DOI] 10.1111/jvim.16571. [PMID] 36254646.
2022
Untargeted global metabolomic profiling of healthy dogs grouped on the basis of grain inclusivity of their diet and of dogs with subclinical cardiac abnormalities that underwent a diet change.
American journal of veterinary research. 83(9) [DOI] 10.2460/ajvr.22.03.0054. [PMID] 35895762.
2021
A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat.
Orphanet journal of rare diseases. 16(1) [DOI] 10.1186/s13023-021-01740-5. [PMID] 33639992.
2021
Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy.
Animal genetics. 52(4):542-544 [DOI] 10.1111/age.13074. [PMID] 33970514.
2021
Correction of serum chloride concentration in dogs with congestive heart failure
Journal of Veterinary Internal Medicine. 35(1):51-57 [DOI] 10.1111/jvim.15998. [PMID] 33305873.
2021
ECG of the Month.
Journal of the American Veterinary Medical Association. 259(4):368-370 [DOI] 10.2460/javma.259.4.368. [PMID] 34337961.
2021
Effect of spironolactone and benazepril on furosemide‐induced diuresis and renin‐angiotensin‐aldosterone system activation in normal dogs
Journal of Veterinary Internal Medicine. 35(3):1245-1254 [DOI] 10.1111/jvim.16097. [PMID] 33713485.
2021
Effect of type of diet on blood and plasma taurine concentrations, cardiac biomarkers, and echocardiograms in 4 dog breeds
Journal of Veterinary Internal Medicine. 35(2):771-779 [DOI] 10.1111/jvim.16075. [PMID] 33638176.
2021
Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016).
Journal of the American Veterinary Medical Association. 259(12):1428-1432 [DOI] 10.2460/javma.20.05.0291. [PMID] 34757932.
2021
Prevalence of an angiotensin-converting enzyme gene variant in dogs
Canine Medicine and Genetics. 8(1) [DOI] 10.1186/s40575-021-00105-2. [PMID] 34256860.
2020
Assessment of PDK4 and TTN gene variants in 48 Doberman Pinschers with dilated cardiomyopathy.
Journal of the American Veterinary Medical Association. 257(10):1041-1044 [DOI] 10.2460/javma.2020.257.10.1041. [PMID] 33135971.
2020
Cross-Sectional Assessment of the Emotional Intelligence of Fourth-Year Veterinary Students and Veterinary House Officers in a Teaching Hospital.
Journal of veterinary medical education. 47(2):193-201 [DOI] 10.3138/jvme.0518-065r. [PMID] 31194633.
2020
Preliminary Evaluation of a Wearable Sensor System for Heart Rate Assessment in Guide Dog Puppies
IEEE Sensors Journal.
2020
Renin‐angiotensin aldosterone profile before and after angiotensin‐converting enzyme‐inhibitor administration in dogs with angiotensin‐converting enzyme gene polymorphism
Journal of Veterinary Internal Medicine. 34(2):600-606 [DOI] 10.1111/jvim.15746. [PMID] 32112596.
2020
Role of electrolyte concentrations and renin‐angiotensin‐aldosterone activation in the staging of canine heart disease
Journal of Veterinary Internal Medicine. 34(1):53-64 [DOI] 10.1111/jvim.15662. [PMID] 31769114.
2020
Visual representations of canine cardiac arrhythmias with Lorenz (Poincaré) plots.
American journal of veterinary research. 81(9):720-731 [DOI] 10.2460/ajvr.81.9.720. [PMID] 33112172.
2019
A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death.
Human genetics. 138(5):515-524 [DOI] 10.1007/s00439-019-01973-2. [PMID] 30715562.
2019
Cardiac Leiomyosarcoma in a Cat Presenting for Bilateral Renal Neoplasia.
Journal of comparative pathology. 168:19-24 [DOI] 10.1016/j.jcpa.2019.02.005. [PMID] 31103054.
2019
Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 21:1-9 [DOI] 10.1016/j.jvc.2018.11.002. [PMID] 30797439.
2019
Myxomatous mitral valve disease in the miniature poodle: A retrospective study.
Veterinary journal (London, England : 1997). 244:94-97 [DOI] 10.1016/j.tvjl.2018.12.019. [PMID] 30825902.
2019
Simultaneous monitoring of canine heart rate and respiratory patterns during scent detection tasks
IEEE Sensors Journal. 19:1454-1462
2018
Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease.
Pharmacogenetics and genomics. 28(2):37-40 [DOI] 10.1097/FPC.0000000000000322. [PMID] 29200408.
2018
Diet-associated dilated cardiomyopathy in dogs: what do we know?
Journal of the American Veterinary Medical Association. 253(11):1390-1394 [DOI] 10.2460/javma.253.11.1390. [PMID] 30451613.
2018
ECG of the Month.
Journal of the American Veterinary Medical Association. 253(6):714-717 [DOI] 10.2460/javma.253.6.714. [PMID] 30179094.
2018
Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration.
Veterinary journal (London, England : 1997). 232:16-19 [DOI] 10.1016/j.tvjl.2017.12.002. [PMID] 29428085.
2018
Pharmacodynamic assessment of diuretic efficacy and braking in a furosemide continuous infusion model.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 20(2):92-101 [DOI] 10.1016/j.jvc.2018.01.003. [PMID] 29483040.
2017
Advances in Feline Cardiac Diagnostics
. 7(6)
2017
Angiotensin-converting enzyme activity and inhibition in dogs with cardiac disease and an angiotensin-converting enzyme polymorphism.
Journal of the renin-angiotensin-aldosterone system : JRAAS. 18(4) [DOI] 10.1177/1470320317737184. [PMID] 29069972.
2017
Furosemide continuous rate infusion diluted with 5% dextrose in water or hypertonic saline in normal adult dogs: a pilot study.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 19(1):44-56 [DOI] 10.1016/j.jvc.2016.09.004. [PMID] 27840084.
2017
Long‐term Stability of a Compounded Suspension of Torsemide (5 mg/mL) for Oral Administration
Journal of Veterinary Internal Medicine. 31(6):1822-1826 [DOI] 10.1111/jvim.14819. [PMID] 28913839.
2015
Effect of atenolol on heart rate, arrhythmias, blood pressure, and dynamic left ventricular outflow tract obstruction in cats with subclinical hypertrophic cardiomyopathy.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 17 Suppl 1:S296-305 [DOI] 10.1016/j.jvc.2015.03.002. [PMID] 26776587.
2015
Relationship of plasma N-terminal pro-brain natriuretic peptide concentrations to heart failure classification and cause of respiratory distress in dogs using a 2nd generation ELISA assay.
Journal of veterinary internal medicine. 29(1):171-9 [DOI] 10.1111/jvim.12472. [PMID] 25308881.
2014
Heart rate and arrhythmia frequency of normal cats compared to cats with asymptomatic hypertrophic cardiomyopathy.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 16(4):215-25 [DOI] 10.1016/j.jvc.2014.10.001. [PMID] 25465341.
2010
Perceptions of quality of life and priorities of owners of cats with heart disease.
Journal of veterinary internal medicine. 24(6):1421-6 [DOI] 10.1111/j.1939-1676.2010.0583.x. [PMID] 20738770.
2010
Successful closure of left-to-right patent ductus arteriosus in three dogs with concurrent pulmonary hypertension.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 12(1):67-73 [DOI] 10.1016/j.jvc.2009.12.002. [PMID] 20188645.
2009
Effect of routine cardiovascular catheterization on cardiac troponin I concentration in dogs.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 11 Suppl 1:S87-92 [DOI] 10.1016/j.jvc.2009.01.002. [PMID] 19395332.
2007
Cardiac evaluation of anesthetized Grevy’s zebras (Equus grevyi).
American journal of veterinary research. 68(2):148-52 [PMID] 17269879.
2007
Papillary muscle measurements in cats with normal echocardiograms and cats with concentric left ventricular hypertrophy.
Journal of veterinary internal medicine. 21(4):737-41 [PMID] 17708393.
2006
Comparison of canine cardiac troponin I concentrations as determined by 3 analyzers.
Journal of veterinary internal medicine. 20(5):1136-42 [PMID] 17063706.
2006
ECG of the Month.
Journal of the American Veterinary Medical Association. 229(1):40-2 [PMID] 16817712.
2006
ECG of the Month. Sinus arrhythmia in an African grey parrot.
Journal of the American Veterinary Medical Association. 229(4):505-7 [PMID] 16910846.
2006
Echocardiographic estimation of systemic systolic blood pressure in dogs with mild mitral regurgitation.
Journal of veterinary internal medicine. 20(5):1127-31 [PMID] 17063704.
2005
Cardiac output measurement by partial carbon dioxide rebreathing, 2-dimensional echocardiography, and lithium-dilution method in anesthetized neonatal foals.
Journal of veterinary internal medicine. 19(5):737-43 [PMID] 16231720.
2005
Cardiac troponin I concentrations in normal dogs and cats using a bedside analyzer.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 7(1):27-32 [DOI] 10.1016/j.jvc.2005.02.001. [PMID] 19083315.
2005
Mitral valve endocarditis after dental prophylaxis in a dog.
Journal of veterinary internal medicine. 19(2):268-70 [PMID] 15822575.
2005
Physiologic valve regurgitation in normal cats.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 7(1):9-13 [DOI] 10.1016/j.jvc.2004.10.001. [PMID] 19083313.
2004
ECG of the month. Atrial fibrillation with a slow ventricular response rate and splintered QRS complexes.
Journal of the American Veterinary Medical Association. 224(8):1258-60 [PMID] 15112773.
2004
The Enlarged Heart
. 42-43
2003
Cardiac troponin I in pastured and race-training Thoroughbred horses.
Journal of veterinary internal medicine. 17(4):597-9 [PMID] 12892316.
2003
Intermittent bolus injection versus continuous infusion of furosemide in normal adult greyhound dogs.
Journal of veterinary internal medicine. 17(5):632-6 [PMID] 14529128.
2003
Short-term compatibility of furosemide with crystalloid solutions.
Journal of veterinary internal medicine. 17(5):724-6 [PMID] 14529143.
2002
Evaluation of three peripheral arteriovenous fistulas for hemodialysis access in dogs.
Veterinary surgery : VS. 31(5):405-11 [PMID] 12209410.
2001
Efficacy of a single oral dose of isorsorbide 5-mononitrate in normal dogs and in dogs with congestive heart failure.
Journal of veterinary internal medicine. 15(2):105-11 [PMID] 11300592.
1999
Balloon dilation of cor triatriatum dexter in a dog.
Journal of veterinary internal medicine. 13(6):617-9 [PMID] 10587266.
1996
Phenylephrine induced ventricular arrhythmias in dogs with inherited sudden death
Journal of Cardiovascular Electrophysiology. 7(3):217-230
1996
Relationship of ventricular tachycardia to sleep/wakefulness in a model of sudden cardiac death
Pediatric Research. 40:344-350
1995
Use of surgical intrauterine insemination to manage infertility in a colony of research German shepherd dogs.
Laboratory animal science. 45(4):404-7 [PMID] 7474880.

Grants

May 2022 – Jun 2024
Circulating surfactant protein B in dogs presenting for acute, decompensated congestive heart failure
Role: Other
Funding: AM COLL OF VET INTERNAL MED
Apr 2022 ACTIVE
Tolerability and clinical efficacy of acetazolamide for treatment of hypochloremia in canine congestive heart failure
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Aug 2021 – Jul 2023
Single Breed Sex Influence on Renin-Angiotensin-Aldosterone System Metabolites and Enzymes: A Pilot Study
Role: Principal Investigator
Funding: TRANSLATIONAL RAAS INTEREST GROUP via CEVA SANTE ANIMALE S.A.
May 2021 – Aug 2021
2021 Summer Veterinary Student Educational Grant – Dana Haimovitz
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Apr 2019 ACTIVE
Investigation into subclinical diet-associated Dilated Cardiomyopathy (DCM) in four dog breeds
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU

Education

Diplomate – Cardiology
2000 · American College of Veterinary Internal Medicine
Residency – Cardiology
1999 · University of California, Davis, CA
Internship
1997 · VCA South Shore Animal Hospital, S. Weymouth, MA
DVM
1996 · Cornell University, Ithaca, NY
BA – Biology
1992 · Hartwick College, Oneonta, NY

Contact Details

Phones:
Business:
(352) 392-2229
Emails:
Business:
adind@ufl.edu
Addresses:
Business Mailing:
PO Box 100116
GAINESVILLE FL 32610
Business Street:
VS-18E
GAINESVILLE FL 32608

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